产品名称 Recombinant Human ACE2 Protein, His-tag
规格 100ug, 1mg
宿主 HEK293 Cells
内毒素水平 < 1.0 EU per μg of the protein as determined by the LAL method.
缓冲体系 Lyophilized from sterile PBS, pH 7.4.
纯化方式 His Tag Purification
产品背景 Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the cell membranes of cells located in the lungs, arteries, heart, kidney, and intestines. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II into angiotensin (1–7). ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang(1-7), making it a promising drug target for treating cardiovascular diseases. ACE2 also serves as the entry point into cells for some coronaviruses, including HCoV-NL63, SARS-CoV, and SARS-CoV-2.
保存条件 Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.