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产品编号: KMP2244
产品名称: Human 5T4 Protein, Avi Tag, His Tag
中文名称: 重组人5T4蛋白
中文全称: 重组人滋养层糖蛋白
关键词: 滋养层糖蛋白, 5T4 Protein, Human 5T4AG Protein, Human M6P1 Protein, Human WAIF1 Protein, Human, Human 5T4 Protein, Avi Tag, His Tag, Recombinant Protein, KMP2244
物种: Human
宿主: HEK293 Cells
规格: 50ug, 100ug, 200ug
纯化方式: Affinity purification
纯度: >95% as determined by SDS-PAGE
内毒素水平: <1.0 EU/ug determined by the LAL method
缓冲体系: PBS, pH7.4
Uniprot: Q13641#structure
SDS-PAGE: KMP2244 SDS-PAGE image1.png
功能: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
产品背景: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap(LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
保存条件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
运输条件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
说明: This product is for research use only.
官网链接: https://www.kmdbioscience.cn/
参考文献: 1 Dev. Cell 21:1129-1143 (2011)
