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通过认证 [诚信档案]
| Cat. Number |
HA4443
|
| Chemical Name |
蒜氨酸,L(+)Alliin
|
| CAS Number |
556-27-4
|
| Mol. Formula |
C6H11NO3S
|
| Mol. Weight |
177.22
|
| Qty 1 |
25mg
|
| Qty 2 |
100mg
|
| Application Notes |
≥98%
|
| Synonym |
3-(2-Propenylsulfinyl) alanine
3-[(S)-2-Propenylsulfinyl]-L-alanine S-Allyl-L-cysteine sulfoxide 3-(Allylsulfinyl)alanin Alliin EINECS 209-118-9 S-Allyl-L-cystein-S-oxid |
| Melting Pt. |
164-166°C
|
| Solubility |
Soluble in water. Insoluble in ethanol, or acetone
|
| Storage condition |
-20℃
|
| References |
L-(+)-Alliin is a cysteine derivative isolated from Allium; it exhibits anti-inflammatory, neuromodulatory, anti-diabetic, anti-hyperlipidemic, antioxidative, cardioprotective, and anti-angiogenic activities; it is the optically active and orally bioavailable isomer of alliin. In adipocytes, L-alliin inhibits LPS-stimulated activation of ERK1/2 and increases in inflammatory signaling. In animal models of myocardial infarction, L-alliin increases activity of superoxide dismutase, glutathione peroxidase, catalase, and glutathione-S-transferase. L-Alliin also activates NMDA-R subunits NR2A and NR2B. In diabetic rats, this compound decreases levels of LDL, VLDL, glucose, triglycerides, total cholesterol, and total lipids. Additionally, L-alliin inhibits VEGF-induced angiogenesis and FGF2 and VEGF secretion in fibrosarcoma cells. |
