N-Octadecanoyl-phytosphingosine

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Chemical Name	N-Octadecanoyl-phytosphingosine
Category	semisynthetic
Mol. Formula	C₃₆H₇₃NO₄
Mol. Weight	584
Qty 1	5mg
Appearance	solid
Application Notes	98+% TLC, MS
Synonym	N-C18:0 Phytoceramide; N-Stearoyl-phytosphingosine
Solubility	chloroform/methanol, 1:1 (warm)
Storage condition	-20°C
References	1. K. Ryu et al. “Anti-scratching Behavioral Effects of N-Stearoylphytosphingosine and 4-Hydroxysphinganine in Mice” Lipids, Vol. 45 pp. 615-618, 2010 2. M. Park et al. “Suppression of Extracellular Signal-related Kinase and Activation of p38 MAPK Are Two Critical Events Leading to Caspase-8- and Mitochondria-mediated Cell Death in Phytosphingosine-treated Human Cancer Cells” Journal of Biological Chemistry, Vol. 278, pp. 50624-50634, 2003 3. F. Omae et al. “DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine” Journal of Biochemistry, vol. 379 pp. 687-695, 2004