     |
通过认证 [诚信档案]
| Cat. Number |
283852753340347
|
| Chemical Name |
环巴胺 Cyclopamine
|
| CAS Number |
[4449-51-8]
|
| Mol. Formula |
C27H41NO2
|
| Mol. Weight |
411.63
|
| Qty 1 |
1mg
|
| Synonym |
(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,1 1bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b- Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo [a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol
|
| Solubility |
Soluble to 5 mM in ethanol
|
| Storage condition |
Desiccate at -20°C
|
| References |
Inhibitor of hedgehog (Hh) signaling, likely via direct inhibition of Smoothened, the accessory protein to the putative Hh receptor Patched. Anti-cancer and teratogenic in vivo. Depletes stem-like cancer cells in glioblastoma and blocks tumor engraftment. |
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